To cite PCAPAM50 in publications, please use:

Raj-Kumar P, Chen B, Hu M, Hohenstein T, Liu J, Shriver C, Lin X, Hu H (2026). “Enhanced PAM50 subtyping of breast cancer implemented in the PCAPAM50 R package.” Scientific Reports, 16(1), 1112. doi:10.1038/s41598-025-30752-5.

Raj-Kumar P, Liu J, Hooke J, Kovatich A, Kvecher L, Shriver C, Hu H (2019). “PCA-PAM50 improves consistency between breast cancer intrinsic and clinical subtyping reclassifying a subset of luminal A tumors as luminal B.” Scientific Reports, 9(1), 7956. doi:10.1038/s41598-019-44339-4.

Parker J, Mullins M, Cheang M, Leung S, Voduc D, Vickery T, Davies S, Fauron C, He X, Hu Z, et al. (2009). “Supervised risk predictor of breast cancer based on intrinsic subtypes.” Journal of Clinical Oncology, 27(8), 1160–1167. doi:10.1200/JCO.2008.18.1370.

The package is available at https://CRAN.R-project.org/package=PCAPAM50. The tool portal is available at https://www.wriwindber.org/tools-portal/pca-pam50/.

Corresponding BibTeX entries:

  @Article{,
    title = {Enhanced PAM50 subtyping of breast cancer implemented in
      the PCAPAM50 R package},
    author = {Praveen-Kumar Raj-Kumar and Boyi Chen and Ming-Wen Hu and
      Tyler Akers Hohenstein and Jianfang Liu and Craig D. Shriver and
      Xiaoying Lin and Hai Hu},
    journal = {Scientific Reports},
    year = {2026},
    volume = {16},
    number = {1},
    pages = {1112},
    publisher = {Nature Portfolio},
    doi = {10.1038/s41598-025-30752-5},
  }

  @Article{,
    title = {PCA-PAM50 improves consistency between breast cancer
      intrinsic and clinical subtyping reclassifying a subset of
      luminal A tumors as luminal B},
    author = {Praveen-Kumar Raj-Kumar and Jianfang Liu and Jeffrey A.
      Hooke and Albert J. Kovatich and Leonid Kvecher and Craig D.
      Shriver and Hai Hu},
    journal = {Scientific Reports},
    year = {2019},
    volume = {9},
    number = {1},
    pages = {7956},
    publisher = {Nature Publishing Group UK London},
    doi = {10.1038/s41598-019-44339-4},
  }

  @Article{,
    title = {Supervised risk predictor of breast cancer based on
      intrinsic subtypes},
    author = {Joel S. Parker and Michael Mullins and Maggie CU Cheang
      and Samuel Leung and David Voduc and Tammi Vickery and Sherri
      Davies and Christiane Fauron and Xiaping He and Zhiyuan Hu and
      {et al.}},
    journal = {Journal of Clinical Oncology},
    year = {2009},
    volume = {27},
    number = {8},
    pages = {1160--1167},
    publisher = {American Society of Clinical Oncology},
    doi = {10.1200/JCO.2008.18.1370},
  }